According to the Centers for Disease Control and Prevention (CDC), a person dies every 37 seconds from cardiovascular disease in the U.S., emphasizing the growing demand for advanced life-support technologies like ECMO systems. Additionally, chronic obstructive pulmonary disease (COPD), one of the leading causes of death in the U.S., continues to fuel market demand. As per the American Lung Association (2022), approximately 4.6% of adults, or 11.7 million people, reported a COPD diagnosis, highlighting the rising burden of respiratory conditions. In response, technological advancements have led to the development of hollow pumps, high-efficiency oxygenators, and heparin-coated cannulas, significantly improving ECMO system performance and versatility in surgical and critical care settings.

The increasing adoption of ECMO systems in hospitals and the expansion of awareness programs have been pivotal in driving market growth. Over the past 3–5 years, more than 100 new ECMO programs have been established in the U.S., bringing the total to around 300–400. This surge reflects growing clinical acceptance and broader access to ECMO therapy. In July 2022, Inspira Technologies OXY B.H.N. Ltd. launched the “Liby” System, a next-generation life support solution for patients suffering from severe heart and lung failure — marking a key milestone in ECMO innovation.

Technological progress has also led to the introduction of portable and compact ECMO machines, making them more adaptable across clinical settings and improving patient transport capabilities. The integration of miniaturized circuits and portable adapters has further expanded ECMO’s applications, especially for critical care transfers and emergency procedures.

Key Market Trends & Insights

North America dominated the market in 2023, holding a 39.5% revenue share.

The U.S. represented the largest share within North America.

By component, the oxygenators segment held the largest share at 34.61% in 2023 and is projected to register the fastest CAGR during the forecast period.

By modality, the veno-arterial segment accounted for the highest revenue share of 42.2% in 2023.

By application, the respiratory segment led the market with a 44.10% share in 2023.

Download a free sample PDF of the Extracorporeal Membrane Oxygenation Machine Market Intelligence Study by Grand View Research.

Competitive Landscape

The ECMO machine market is characterized by a competitive mix of established players and emerging innovators. Leading companies are focusing on technological innovation, global expansion, and AI integration to enhance patient outcomes and broaden clinical applications. The demand for portable, smart, and telemedicine-integrated ECMO systems is shaping the next phase of market evolution. Established firms are also expanding into emerging regions to meet the growing demand for advanced life support solutions.